1H-Pyrazole-5-carboxylic acid, 3-amino-1-methyl-, methyl ester - Names and Identifiers
1H-Pyrazole-5-carboxylic acid, 3-amino-1-methyl-, methyl ester - Physico-chemical Properties
Molecular Formula | C6H9N3O2
|
Molar Mass | 155.15 |
Storage Condition | 2-8℃ |
1H-Pyrazole-5-carboxylic acid, 3-amino-1-methyl-, methyl ester - Upstream Downstream Industry
1H-Pyrazole-5-carboxylic acid, 3-amino-1-methyl-, methyl ester - Introduction
METHYL-3-AMINO-1-METHYL PYRAZOLE-5-CARBOXYLATE is an organic compound with the chemical formula C6H8N4O2.
Nature:
-Appearance: METHYL-3-AMINO-1-METHYL PYRAZOLE-5-CARBOXYLATE is a white to pale yellow crystalline solid.
-Melting point: About 75-77 ℃.
-Solubility: Soluble in organic solvents such as ethyl acetate, methanol and dimethylformamide.
Use:
METHYL-3-AMINO-1-METHYL PYRAZOLE-5-CARBOXYLATE is commonly used as an intermediate in organic synthesis and has a wide range of applications in the fields of medicine, pesticides and dyes. It can be used to synthesize a variety of drugs and compounds containing pyrazole ring, such as antiviral drug ribavirin and chemotherapy drug ciprofloxacin.
Method:
The preparation of METHYL-3-AMINO-1-METHYL PYRAZOLE-5-CARBOXYLATE is generally carried out by the following steps:
1. The methyl pyrazole and chloroformate are reacted in the presence of a base to generate 3-methoxycarbonylmethylpyrazole.
2. Hydrolyze 3-methoxycarbonylmethylpyrazole with ammonia or other ammonia sources to generate METHYL-3-AMINO-1-METHYL PYRAZOLE-5-CARBOXYLATE.
Safety Information:
The specific safety information of METHYL-3-AMINO-1-METHYL PYRAZOLE-5-CARBOXYLATE needs to be determined according to the specific situation. As an organic compound, attention should be paid to its protection and safety measures during handling and storage. Use with appropriate protective gloves and eye protection and avoid inhalation or contact with skin. Should be stored in a closed container, away from fire and heat sources. For specific safety instructions, please refer to the safety technical specifications of the chemical or consult the relevant experts.
Last Update:2024-04-09 02:00:50